Neuroscience Information Framework
Short Resource Summary
| Short Name | neuroConstruct |
| Name | neuroConstruct: Biophysical Neural Network Modeling Software |
| Nif Id | nif-0000-00105 |
| Entry Date | |
| Urls | www.neuinfo.org/registered_resources.shtm |
| Parent Organization | University College London; London; United Kindom |
| Resource Types | simulation software (birnlex_2346) |
| Keywords | analysis, biological, cell, cellular, channel, conductance, data, dendrite, java, mechanism, membrane, model, morphology, network, neuron, neuroscience, pharmacology, physiology, simulation, software (nlx_res_20090103), synapse, visualization |
| Comments | Type: resource_comment neuroConstruct is cross-platform Java software for simulating complex networks of biologically realistic neurons. neuroConstruct is being developed in the Silver Lab in the Department of Neuroscience, Physiology and Pharmacology at UCL. It has been designed to simplify development of complex networks of biologically realistic neurons, i.e. models incorporating dendritic morphologies and realistic cell membrane conductances. It is implemented in Java and generates script files for the NEURON and GENESIS simulators, with support for other simulation platforms (including PSICS and PyNN) in development. It uses the latest NeuroML specifications, including MorphML, ChannelML and NetworkML. Some of the key features of neuroConstruct are: Creation of networks of biologically realistic neurons, positioned in 3D space. Complex connectivity patterns between cell groups can be specified for the networks.neuroConstruct can import morphology files in GENESIS, NEURON, Neurolucida, SWC and MorphML format for inclusion in network models.Simulations can be run on the NEURON or GENESIS platforms. Cellular processes (synapses/channel mechanisms) can be imported from native script files or created in ChannelML. Recording of simulation data generated by the simulation and visualization/analysis of data in neuroConstruct. Stored simulation runs can be viewed and managed through the Simulation Browser interface. Target of this tool is the computational neuroscience community. In particular anyone interested in creating and visualizing large neuronal networks with NEURON. NEURON is required to actually perform the simulations. Sponsors: Development of this software was made possible with funding from the Medical Research Council and the Wellcome Trust |
