One Mind: One Voice Bio-repository Cosmic Landscape

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Condition
Description	Database containing the DNA sequence and annotation of the entire human chromosome 7, encompassing nearly 158 million nucleotides of DNA and 1917 gene structures, are presented; the most up to date collation of sequence, gene, and other annotations from all databases (eg. Celera published, NCBI, Ensembl, RIKEN, UCSC) as well as unpublished data. To generate a higher order description, additional structural features such as imprinted genes, fragile sites, and segmental duplications were integrated at the level of the DNA sequence with medical genetic data, including 440 chromosome rearrangement breakpoints associated with disease. The objective of this project is to generate a comprehensive description of human chromosome 7 to facilitate biological discovery, disease gene research and medical genetic applications. There are over 360 disease-associated genes or loci on chromosome 7. A major challenge ahead will be to represent chromosome alterations, variants, and polymorphisms and their related phenotypes (or lack thereof), in an accessible way. In addition to being a primary data source, this site serves as a weighing station for testing community ideas and information to produce highly curated data to be submitted to other databases such as NCBI, Ensembl, and UCSC. Therefore, any useful data submitted to us will be curated and shown in this database.
Type	database, data storage repository, biomaterial supply
NIF ID	See Full Record: nif-0000-03550
Name	Chromosome 7 Annotation Project
Additional Info.
Organism	Human
Keywords	duplication, expression data, family, fish, gene, gene annotation, genome, breakpoints, chromosome, chromosome 7, clinical, deletion, disease genes, dna sequence, human, insertion, inversion, polymorphism, rearrangements, segmental duplication, snp, translocation

Condition	Healthy control, Autism, Cystic fibrosis, Epilepsy, Polymorphism
Description	Service and training support for academic, government, and private sector scientists worldwide in genomics, including laboratory experimentation, statistical analysis, and comprehensive bioinformatics support, including large-scale genome comparisons, algorithm and tools development, and database curation, annotation and hosting. The Centre for Applied Genomics hosts a variety of databases related to ongoing supported projects: *Autism Chromosome Rearrangement Database *Cystic Fibrosis Mutation Database *The Lafora Progressive Myoclonus Epilepsy Mutation and Polymorphism Database *Database of Genomic Variants *The Chromosome 7 Annotation Project *Human Genome Segmental Duplication Database *Non-Human Segmental Duplication Database Healthy control DNA samples from the Ontario Population Genomics Platform are available. The Biobanking and Databasing Facility provides DNA extraction from lymphoblasts, fibroblasts and other cell types, archiving of white cell pellets, preparation and immortalization of cell lines, and comprehensive databasing and tracking of samples and/or cell lines within the facility.
Type	Database, Biomaterial analysis service, Biomaterial manufacture, Topical portal, Training service resource,
NIF ID	See Full Record: nif-0000-12519
Name	TCAG
Additional Info.	Sample type: DNA;
Organism	human, mouse, non-human animal
Keywords	genomics, publication, link, bioinformatics, genome, research, Microarray analysis, gene expression, genotyping, Biobanking, Statistical analysis, Genetic analysis, Cytogenomics, DNA sequencing, DNA synthesis, comparative genomic hybridization, Karyotyping, FISH Mapping, human, mouse, gene expression, biobanking, DNA, mutation, Genomic variant, Chromosome 7

Condition
Description	RUCDR is a biobank and a service organization that maintains human blood, serum, saliva, tissue and the genetic products derived from those. Services include technical consultation and logistical support for biobanking. Researchers can order biomaterials and apply for phenotypic / genotypic data.
Type	Biomaterial supply resource, Cell repository, Data resource
NIF ID	See Full Record: nlx_60990
Name	Rutgers Cell and DNA Repository
Additional Info.	Sample type: Cell, DNA, Blood, Cell line; Availability: Researchers can order biomaterials and apply for phenotypic / genotypic data, depending on the project.; Application: Research;
Organism	Human
Keywords	Genetics, Disease, Phenotypic data, Genotypic data, Cell, DNA, Blood, Cell line

Condition
Description	Database of mouse strains and stocks available worldwide, that will assist the international research community in finding the mouse resources they need, including inbred, mutant, and genetically engineered mice. The IMSR is a multi-institutional international collaboration supporting the use of the mouse as a model system for studying human biology and disease. The IMSR began with an initial collaboration between the Mouse Genome Informatics (MGI) group at The Jackson Laboratory and the Medical Research Council Mammalian Genetics Unit at Harwell. Additional institutions and collaborators are now contributing mouse resource information to the IMSR. The data content found in the IMSR is as it was supplied by data provider sites. You are encouraged to participate in making this database as complete as possible for all worldwide mouse strain resources. If you or your institution hold mice, cryopreserved gametes or embryos, or ES cell lines that you distribute to other researchers, contributing information about them to the IMSR catalog will make them more widely known.
Type	Organism supplier, Cell repository
NIF ID	See Full Record: nif-0000-09876
Name	International Mouse Strain Resource
Additional Info.	Sample type: live mouse, Embryo, gamete, Embryonic stem cell line, Ovary, Sperm, germplasm; Availability: Public, The community can contribute to this resource.; Processing: Cryopreserved, Freeze-dried; Application: Research; Grant: LM009693; Funding: National Library of Medicine; Reference: 10098412
Organism	Mouse
Keywords	Mouse, Strain, Stock, Inbred, Mutant, Genetically engineered, Embryo, Embryonic stem cell line, Database, knockout mouse, mutant mouse strain, transgenic mouse, Embryonic mouse, live mouse, gamete, Ovary, Sperm, germplasm, model organism

Condition
Description	Project to improve data and sample exchanges and to facilitate large scale analysis of data by improving interoperability of French Biological Resources Centres (BRC or biobanks) IT systems and biological databases. The work done in this project will be linked to other national (IBiSA, ANR, R��seau des Biobanques, Club 3C-R), European (BBMRI, ELIXIR) or international project (P3G). In the preliminary phase (2009-2010) I3-CRB has developed a directory of French Biological Resource Centres / Biobanks where one may register their French BRC or perform a search across all of them. Detail by overall data or kingdom is provided as well as many filtering options. Access to biological samples is provided by the participating BRC's. Biological Resources Centres (BRC or biobanks) collect annotated biological samples from various sources (human, animal, plant, bacteria...). The type of samples depends on the collection and the associated thematic (DNA, proteins, cells, tissues, blood, serum, organisms...). The aims of these centers are to collect, to store, to transform and to distribute the biological samples. They constitute a vital infrastructure for life science and health research. Goals of the French Biobanks/Biological Resource Centres: * List French biobanks and their biological collections * Improve sample exchanges * Improve the international visibility of the French biological collections MeSH terms have been integrated: Domains, diseases, and location of the disease (Anatomy). Collections/species are based on NCBI Taxonomy.
Type	Topical portal, Data set, Biomaterial supply resource
NIF ID	See Full Record: nlx_36068
Name	I3-CRB: Interoperable IT Infrastructure for Biological Resources Centres / Biobanks - France
Additional Info.	Sample type: DNA, Protein, Cell, Tissue, Blood, Serum, Organism, etc.; Availability: Varying: Access to biological samples is provided by the participating BRC's., The community can contribute to this resource.; Application: Research; Funding: GIS IBiSA;
Organism	Human, Non-human animal, Plant, Microorganism
Keywords	Plant, Animal, Human, Micro-organism, Microorganism, Bacteria, DNA, Protein, Cell, Tissue, Blood, Serum, Organism, Research

Condition	Alzheimer's disease, Late-onset Alzheimer's disease, Dementia, Normal, Memory loss
Description	A national repository for Alzheimer's disease that collects and maintains biological specimens and associated data on large numbers of genetically informative, phenotypically well-characterized families with multiple individuals affected with Alzheimer's disease, as well as individuals for case-control studies. Qualified research scientists may apply to NCRAD for samples and data to conduct genetic research. NCRAD is located at Indiana University. It is the policy of the National Institute on Aging (NIA) that useful specimens and Associated Phenotypic Data for the genetics of late-onset Alzheimer's disease be deposited at NCRAD whenever possible. Associated Phenotypic Data is defined as deidentified data on family structure, age, sex, vital status, psychopathology, diagnosis, and other clinically relevant associated phenotypic information, stripped of all personal identifiers and thus unlinkable to the individuals from whom they were obtained.
Type	Tissue bank, Biomaterial supply resource, Biospecimen repository, Data repository
NIF ID	See Full Record: nif-0000-00178
Name	National Cell Repository for Alzheimers Disease
Additional Info.	Sample type: DNA, Plasma, Serum, RNA, Brain tissue, Cell line, Blood; Availability: Public, application required for genetic research.; Application: Research; Funding: NIA, NIH Blueprint for Neuroscience Research;
Organism	Human
Keywords	gene, genetic research, Alzheimer's disease, clinical, control, dementia, DNA, late onset Alzheimer's disease, memory loss, normal, phenotypic data, research study, Late adult human, Cell line, Clinical data, Plasma, Serum, RNA, Brain tissue, Phenotype, family history, Blood

Condition
Description	A global nonprofit biological resource center and research organization that provides biological products, technical services and educational programs to private industry, government and academic organizations. Its mission is to acquire, authenticate, preserve, develop and distribute biological materials, information, technology, intellectual property and standards for the advancement and application of scientific knowledge. The primary purpose of ATCC is to use its resources and experience as a BRC to become the world leader in standard biological reference materials management, intellectual property resource management and translational research as applied to biomaterial development, standardization and certification. ATCC serves U.S. and international researchers by characterizing cell lines, bacteria, viruses, fungi and protozoa, as well as developing and evaluating assays and techniques for validating research resources and preserving and distributing biological materials to the public and private sector research communities. Deposit Services: Redundant storage is essential for the long-term preservation of biological materials. For over 30 years, ATCC has provided secure and reliable deposit services supporting basic to applied research * BioProducts: Cell, microbial and molecular genomics products for the life sciences * BioServices: Bio-materials management; basic repository to complex partnership level services * BioStandards: Biological Reference Material and Consensus Standards for the life science community
Type	Material storage repository, Antibody supplier,
NIF ID	See Full Record: nif-0000-10159
Name	ATCC
Additional Info.
Organism
Keywords	biomaterial, cell, cell line, culture, disease, genomics, in vitro, material, microorganism, proteomics, product, protozoa, tissue, bacteria, biomaker

Condition	Healthy control, Aging, Alzheimer's disease, Neurological disease, Parkinson's disease, Frontotemporal dementia, Pick's disease, Primary Progressive Aphasia, Dementia with Lewy bodies, Dementia, Progressive Supranuclear Palsy, Corticobasal Degeneration, Vascular dementia, Cerebral Amyloid Angiopathy, Dementia pugilistica, Boxer's Syndrome, Neurodegenerative disease
Description	The mission of the Massachusetts Alzheimer's Disease Research Center is To support new research and to enhance ongoing research by providing core support to bring together behavioral, biomedical, and clinical science investigators in a manner that will enrich the effectiveness of Alzheimer disease research and ultimately, improve health care delivery...to foster three related functions: Conducting multi-disciplinary research; training scientists and clinicians; and teaching and/or transferring new information concerning Alzheimer disease and related disorders. The Massachusetts ADRC was officially established on September 28, 1984 by our Founding Director, Dr. John H. Growdon, and it remains one of the two original ADCs (the other being the ADRC at the University of California at San Diego) that have been continually funded by the National Institute on Aging since the ADC program inception. The principal goal of the Massachusetts ADRC is to stimulate and support research of the highest quality in aging, Alzheimer's Disease and related disorders. Our researchers work with national and international multi-disciplinary teams to understand normal aging, and the transition from normal aging to mild forms of memory problems, to the later stages of dementia. Many of our research projects are also coordinated through the National Institute on Aging's National Alzheimer's Coordinating Center. The Massachusetts ADRC has an active brain donation program at the Massachusetts General Hospital (MGH) for subjects enrolled in our research studies and patients of the MGH. Our brain donation program welcomes enquiries from healthy donors as well as those with neurological diseases such as Alzheimer's disease; Parkinson's disease; frontotemporal dementias (including Pick's disease & Primary Progressive Aphasia (PPA)); dementia with Lewy bodies; other Parkinsonian diseases (including Progressive Supranuclear Palsy (PSP) and Corticobasal Degeneration (CBD)); vascular dementias (including Cerebral Amyloid Angiopathy (CAA)); dementia pugilistica (Boxer's Syndrome) and other rarer forms of neurodegenerative disorders. All samples are distributed in a completely de-identifed manner, keeping the identities of donors to our program confidential. The decision to participate is usually made jointly by the patient and family. You may make enquiries through the Neuropathology Service at the MGH (Tel: 617-726-5156). As a specialized research center funded by the United States Department of Health and Human Services, the Massachusetts Alzheimer's Disease Research Center welcomes you to learn more about the extensive research, training and outreach programs that are offered, and we hope that you will join us in our efforts to discover effective treatments and an eventual cure for Alzheimer's disease.
Type	Brain bank, Disease-related portal,
NIF ID	See Full Record: nlx_144104
Name	Massachusetts Alzheimers Disease Research Center
Additional Info.	Sample type: Brain tissue, Brain, Tissue; Application: Research; Funding: U.S. Department of Health and Human Services, NIA;
Organism	Human
Keywords	Brain tissue, Brain, Tissue, Healthy control, Aging, Alzheimer's disease, Neurological disease, Parkinson's disease, Frontotemporal dementia, Pick's disease, Primary Progressive Aphasia, Dementia with Lewy bodies, Dementia, Progressive Supranuclear Palsy, Corticobasal Degeneration, Vascular dementia, Cerebral Amyloid Angiopathy, Dementia pugilistica, Boxer's Syndrome, Neurodegenerative disease, Late adult human

Condition	Autism, Autism spectrum disorder, Pervasive Development Disorder
Description	World's largest private repository of clinical and genetic information on families with autism. Genetic and clinical data are obtained from families that have more than one family member diagnosed with an Autism Spectrum Disorder. The biological samples, along with the accompanying clinical data, are made available to AGRE-approved researchers worldwide. As they become available, additional family pedigrees will be posted in the online catalog which, based on the expanding nature of the resource, provides the most up-to-date availability of pedigrees and biomaterials. Cell lines have been established for the majority of families in this collection and serum/plasma is available on a subset of the subjects until stocks are depleted. The diagnosis of autism has been made using the standard Autism Diagnostic Interview-Revised (ADI-R) algorithm and the Autism Diagnostic Observation Scale (ADOS-G). Detailed birth and medical histories (including basic dysmorphology assessments) on children as well as family and medical information for parents and unaffected siblings, are available for nearly all families. These data continue to be collected for the remainder of the catalog families. To obtain access to the AGRE collection, researchers must receive approval from the AGRE Steering Committee by completing the Researcher Access application and the signing of the Researcher Distribution Agreement found on the AGRE website. DNA, cell lines, serum, plasma and clinical information are made available to AGRE-approved researchers for analysis.
Type	Database, Biomaterial supply resource, Biospecimen repository, Cell repository
NIF ID	See Full Record: nif-0000-00226
Name	Autism Genetic Resource Exchange
Additional Info.	Sample type: DNA, Cell line, Serum, Plasma; Availability: Public: The biological samples, along with the accompanying clinical data, are made available to AGRE-approved researchers worldwide., The community can contribute to this resource.; Processing: Frozen; Application: Research; Grant: 1U24MH081810; Funding: National Institute of Mental Health;
Organism	Human
Keywords	Phenotyping, Evaluation, Family registry, Gene bank, Genetic biomaterial, Genetics, Autism Diagnostic Interview Revised, Autism Diagnostic Observational Scales, Assessment, Autism, Autism diagnostic observation schedule, Autism spectrum disorder, Birth, Clinical data, Genetic data, Diagnoses, Genome scan, Genotypic data, Medical history, Pedigree, Phenotypic data, DNA, Cell line, Serum, Plasma, Biorepository, Biospecimen, Pervasive Development Disorder, Phenotype, Frozen, Clinical, Genetic

Condition	Human immunodeficiency virus, AIDS, Seronegative control, Normal control
Description	THIS RESOURCE IS NO LONGER IN SERVICE, documented on March 23, 2012. The National Neurologic AIDS Bank (NNAB) is a site of the HIV/CNS Tissue Network. Based in Los Angeles, which has the largest and most diverse AIDS population in the western United States, the NNAB provides researchers with well-characterized neural tissue from HIV-1-infected and seronegative control donors. The NNAB collaborates with the other designated sites, funding agencies, and outside experts to develop local and national tissue networks. There are plans to create a Network Steering Committee, a panel of outside advisers, and a protocol to recruit and characterize human donors. The NNAB collects pre- and post-mortem clinical data and neural tissues using a standardized autopsy protocol, and the bank stores, codes, catalogs, and distributes this tissue. An electronic database and an Internet-based application process that researchers can use to access the Network's resources are being designed.
Type	Tissue bank, Data resource
NIF ID	See Full Record: nlx_12023
Name	National Neurological AIDS Bank
Additional Info.	Sample type: Neural tissue, Tissue; Availability: Public: The NNAB collects pre- and post-mortem clinical data and neural tissues using a standardized autopsy protocol, and the bank stores, codes, catalogs, and distributes this tissue., THIS RESOURCE IS NO LONGER IN SERVICE, documented on March 23, 2012.; Application: Research;
Organism	Human
Keywords	Human immunodeficiency virus, AIDS, Seronegative control, Normal control, Neural tissue, Clinical data, Pre-mortem, Post-mortem, Tissue

Condition	Normal, Disease, Healthy
Description	The da Vinci European BioBank collects, stores, processes and distributes biospecimens and the associated data. The biospecimens are human and non-human genetic materials, proteins, cells, tissues and biofluids. The data are the biological information associated to the samples and, in the case of human samples, the clinical information pertaining to the donor. The da Vinci European BioBank (daVEB) is a multicenter biobank with a centralized IT infrastructure and a main repository located at the Polo Scientifico (Scientific Campus of the University of Florence) in Sesto Fiorentino (Florence, Italy). Hosted by the Magnetic Resonance Center (CERM), an expert center on protein structure and metabolomics, daVEB's aim is to host as rich as possible biological human sample collections, stored accordingly to EU guidelines, in order to offer a powerful tool in the study of complex diseases. At the end of July 2011, the da Vinci European BioBank of the Pharmacogenomics FiorGen Onlus Foundation has been audited and got the quality certification according to UNI EN ISO 9001:2008 for Collection, storage and distribution of biological samples and the associated data for scientific research. Besides the samples stored at da Vinci European BioBank in Sesto Fiorentino (Florence), the daVEB is also the administrative biobank for research sample collections that are stored in the delocalized repositories. All the sample collections must be registered in the biobank: * sample collections taken within the regular health care * samples taken from healthy individuals or other persons out of the regular health care * samples that have been taken in hospitals within research protocols on specific pathologies all transferred to daVEB endowed with a transfer agreement signed by the donor. The Research Units actually afferent to daVEB are delocalized in the Florence, Prato, Pisa and Siena provinces. Delocalized repositories are under construction in Tuscany.
Type	Biomaterial supply resource, Data resource
NIF ID	See Full Record: nlx_87590
Name	da Vinci European Biobank
Additional Info.	Sample type: Serum, Plasma, Urine, Buffy coat, White cell, Blood, Peripheral blood, DNA, Whole blood, Tissue, RNA, Cell, Bone marrow, Protein, Bodily fluid; Processing: Frozen, Snap frozen; Application: Research;
Organism	Human, Non-human animal
Keywords	protein structure, metabolomics, Complex disease, Clinical data

Condition	Rare disease, Disease
Description	Database of biospecimens collected, stored, and distributed by biorepositories in the United States and around the globe. Goals # To help and assist interested parties and investigators search, locate, and identify desired biospecimens needed for their research. # To facilitate collaboration and sharing of material and data among investigators across the globe. # To accelerate research to facilitate the discovery of new treatments, therapeutics and eventually cures for rare diseases as well as common diseases. # To identify, locate and increase the awareness of existing biorepositories across the globe. # To link the RD-HUB with the Global Rare Diseases Patient Registry and Data Repository (GRDR). To learn more about GRDR, view the following link : http://rarediseases.info.nih.gov/GRDR. To view biospecimens available from the participating repositories, search the Human Biospecimens/Biorepositories Database by clicking on the Search the Database button and then click on the Repository tab. A list of repositories will be displayed for you to choose from or you may search All.
Type	Database, Biomaterial supply resource
NIF ID	See Full Record: nlx_143682
Name	Biospecimens/Biorepositories: Rare Disease-HUB (RD-HUB)
Additional Info.	Availability: Public., The community can contribute to this resource.; Application: Research; Funding: NIH,;
Organism	Human
Keywords	Rare disease, Disease, Public

Condition
Description	THIS RESOURCE IS NO LONGER IN SERVICE, documented on September 15, 2011. The Spanish HIV BioBank was created with the objectives of processing, storing and providing distinct samples from HIV/AIDS patients, categorized according to strictly defined characteristics, free of charge to research projects. Strict compliance to ethical norms is always guaranteed. HIV BioBank possesses nearly 50,000 vials containing different prospective longitudinal study sample types. More than 1,700 of these samples are now used in 19 national and international research projects. (2009) The HIV BioBank represents a novel approach to HIV research that might be of general interest not only for basic and clinical research teams working on HIV, but also for those groups trying to establish large networks focused on research on specific clinical problems. It also represents a model to stimulate cooperative research among large numbers of research groups working as a network on specific clinical problems. The HIV BioBank is able to very efficiently release samples to different research project not only in Spain but also in other countries.
Type	Biomaterial supply resource
NIF ID	See Full Record: nlx_68685
Name	HIV Biobank
Additional Info.	Availability: THIS RESOURCE IS NO LONGER IN SERVICE, documented on September 15, 2011.; Grant: FIS PI061479, RETIC RD06/0006/0035, 36514/05, 36536/05; Funding: Fondos de Investigacion Sanitaria, Red Tematica de Investigacion Cooperativa Sanitaria ISCIII, Fundacion para la Investigacion y Prevencion del SIDA en Espana, Fundacion Caja Navarra; Reference: 19272145
Organism	Human
Keywords

Condition	All
Description	World's open biospecimen research database where biobanks and biomedical researchers meet to exchange human biospecimen needs and supply: whole blood, serum, plasma, solid tissue samples and more. The connection is accelerated so researchers save valuable time and money and tissue banks utilize inventory. The pace of specimen procurement remains unacceptably slow to the biomedical research community. Specimen Central is the foremost global resource to aid biomedical researchers in expediting their search for high quality human biospecimens, tissues, samples and specimens. They facilitate your search for blood, whole blood, buccal swab, DNA, RNA, protein, cell lines, plasma, serum, RBC, white cells, buffy coat, fluid, marrow, urine, stem cells, and solid tissue such as tumor, tumor and biopsy materials spanning all manner of common and rare pathologies and indications including Alzheimer's, basal cell carcinoma, bladder cancer, bone cancer, brain cancer, breast cancer, cerebrospinal fluid, amniotic fluid, colorectal cancer, colon cancer, hodgkins and non-hodgkins lymphoma, kidney/renal cancer, leukemia, liver cancer, lung cancer, melanoma, multiple sclerosis, myeloma neuroblastoma, neurodegenerative diseases, ovarian cancer, pancreatic cancer, prostate cancer, urinary cancer. This includes adult and pediatric indications. Specimen Central users specify a number of variables in their Specimen Requests, including preparation, preservation and handling requirements such as cryo-preserved, FFPE (Formalin-fixed paraffin-embedded), formalin, frozen, refrigerated, OCT, snap frozen, paraffin block, fresh, prospective, autopsy or cadaveric, etc. Many users require clinically annotated date associated with their specimens, as well as documentation of IRB or ethics committee approval and informed consents. For Researchers Most specimen databases require researchers to waste time and effort entering lengthy registrations and search queries that yield poor results, if anything. Specimen Central solves this problem by having tissue banks search for you. From years to months, months to weeks, and weeks to days, Specimen Central seeks to reduce delays and costs in the research & development life cycle by expediting connections between demand and supply. For Biobanks The capital costs of maintaining a biobank infrastructure are substantial and growing. Biobanks use Specimen Central as a marketing tool to augment their business development efforts. By routinely checking Specimen Central's Specimen Requests, biobanks can uncover market demand for their inventories and develop new connections and revenue streams to defray costs. Specimen Central supplements - not displaces - the efforts of your sales representatives, agents, brokers and commercial partners.
Type	Database, Biomaterial supply resource,
NIF ID	See Full Record: nlx_10317
Name	SpecimenCentral.com
Additional Info.	Sample type: Blood, Tissue, Cell, DNA, RNA, Protein, Body fluid, whole blood, buccal swab, Cell line, plasma, serum, Red Blood Cell, white cell, buffy coat, Marrow, urine, stem cell, Solid tissue, tumor, Tissue; Availability: The community can contribute to this resource.; Processing: Cryopreserved, Formalin-fixed paraffin-embedded, Formalin, Frozen, Refrigerated, OCT, Snap frozen, Paraffin block, Fresh, Prospective, Autopsy, Cadaveric, etc; Application: Research;
Organism	Human
Keywords	blood, tissue, cell, DNA, RNA, Protein, Body fluid, whole blood, buccal swab, Cell line, plasma, serum, Red Blood Cell, white cell, buffy coat, Marrow, urine, stem cell, Solid tissue, tumor, adult, pediatric, biopsy material, child, clinically annotated, clinical, annotated, Tissue

Condition	Parkinson's disease
Description	THIS RESOURCE IS NO LONGER IN SERVICE, documented on April 26, 2011. Information for depositors Investigators who are willing to share mice with the PD research community through this resource should send an email to PDMice_at_ninds.nih.gov describing the mouse. The submission will be reviewed by the PD Models Repository Oversight Committee and, if accepted, a copy of the MTA will be sent by return email. NINDS is most interested in distributing mice that have been characterized in a peer-reviewed publication, but other models will certainly be considered. The email should describe the following: The protocol for identification from tail DNA. The health report of the mice to be shipped (the report has to be less than 2 months old). Information about the strain and any special needs for care and breeding. Information about any publications involving the mice Certification that mice are not encumbered by continuing intellectual property or other rights to any research, data or discovery utilizing the animals. Information for consumers Investigators desiring to study the mice available through the repository should send a request via email to PDMice_at_ninds.nih.gov. Requests will be reviewed by the PD Models Repository Oversight Committee and priority will be determined on a first come, first served basis; two breeding pairs will typically be shipped to any single requester. As detailed in the MTA, mice are not available for commercial research, including but not limited to drug screening. Neither the creator nor UCLA have a role in the governance of the Repository, and specifically, cannot impose conditions upon availability or distribution. It is anticipated that until the Repository is in a mode of steady state production, requests will be collected and mice distributed as supply allows. The email requesting mice should include: A brief description of the protocol Either a copy of the IACUC approval letter or numberNINDS/UCLA Repository for Parkinson's Disease Mouse Models: One of the most immediate and important benefits of discoveries regarding the genetic or environmental causes of Parkinson's disease (PD) is the subsequent development of animal models wherein therapeutic and/or preventative interventions may be studied. The widespread availability of such models is critically important to making progress against a disorder that affects more than 500,000 Americans at any given time. The National Institute of Neurological Disorders and Stroke (NINDS) fully recognizes the burden placed on investigators by the financial and logistical realities of distributing high demand research resources. Some investigators have deposited their mice with national distribution facilities but many mouse models are not available through such resources. Developing means to facilitate greater sharing of mouse models of PD is one of the goals developed by the PD research community at the July 2002 summit meeting convened by the NIH Director. Accordingly, as part of the effort to accelerate PD research, NINDS and the University of California at Los Angeles (UCLA) created a resource that will distribute transgenic mouse models of human PD that are not yet available through national commercial resources. Investigators who are willing to share mice with the PD research community can simply arrange with NINDS to have the mice deposited at UCLA and investigators desiring to study the mice may arrange with NINDS to obtain two breeding pairs. The process will use Material Transfer Agreements created specifically for this arrangement.
Type	Organism supplier, Database, Biospecimen repository
NIF ID	See Full Record: nif-0000-00187
Name	NINDS/UCLA Repository for Parkinson's Disease Mouse Models
Additional Info.	Availability: THIS RESOURCE IS NO LONGER IN SERVICE, documented on April 26, 2011.; Funding: NINDS;
Organism	Mouse
Keywords	fbv x 129/sv, fvb/n, 129s4 mix, 129s6/svev, -/-a53t/pac tg alpha, alpha synuclein knockout, bl6, dj-1 knockout, mt human alpha synuclein (a53t), parkin 129s4, synuclein, Mouse model

Condition	AIDS, AIDS related malignancy
Description	THIS RESOURCE IS NO LONGER IN SERVICE, documented on February 27, 2012. The National Cancer Institute established centers in the United States and its territories for the collection and distribution of tissues, blood and secretions from patients with clinically-characterized AIDS related malignancies in 1994. The AIDS Malignancy Bank makes these tissues available to qualified investigators in the United States for research on AIDS malignancies. It is hoped that by providing access to these high-quality specimens, research in AIDS-related malignancies will be encouraged and expanded. The AMB contains formalin-fixed paraffin-embedded tissues, fresh-frozen tissues, malignant-cell suspensions, fine-needle aspirates, and cell lines from AIDS-related malignancies. The bank also contains serum, plasma, urine, bone marrow, cervical secretions, anal swabs, saliva semen and multi-site autopsy tissues from patients with AIDS-related malignancies who have participated in clinical trials. The bank has an associated database that contains prognostic, staging, outcome and treatment data on patients from whom tissues were obtained. Researchers pay for preparation and shipping of specimens.
Type	Tissue bank, Biomaterial supply resource, Cell repository, Database,
NIF ID	See Full Record: nlx_143727
Name	AIDS Malignancy Bank
Additional Info.	Sample type: Tissue, Blood, Bodily fluid, Malignant-cell, Cell line, Serum, Plasma, Urine, Bone marrow, Cervical secretion, Anal swab, Saliva, Semen,; Availability: Public (USA): Available to qualified investigators in the United States for research on AIDS malignancies., THIS RESOURCE IS NO LONGER IN SERVICE, documented on February 27, 2012.; Processing: Formalin-fixed paraffin-embedded, Fresh-frozen, Suspension, Frozen; Application: Research; Funding: NCI,;
Organism	Human
Keywords	Tissue, Blood, Bodily fluid, Malignant-cell, Fine-needle aspirate, Cell line, Serum, Plasma, Urine, Bone marrow, Cervical secretion, Anal swab, Saliva, Semen, Autopsy, Clinical data, Formalin-fixed paraffin-embedded, Fresh-frozen, Frozen, Suspension, AIDS, AIDS related malignancy

Condition
Description	Public data warehouse for searching cell line data extracted from both ATCC and HyperCLDB. The knowledge base uses the Cell Line Ontology, created with the Protege ontology editing tool from the National Center for Biomedical Ontologies (NCBO) and merges concepts from other ontologies, including the Cell Type Ontology. The Cell Line Knowledge Base uses our Cell Line Ontology as the underlying data model. The ontology defines the following cell line attributes: Cell Line ID, Organism, Tissue, Pathology, Growth Mode, MeSH ID. To report errors in the data or to add cell line data to the knowledge base, please email: clbk-data (at) umich.edu
Type	Database, Cell repository
NIF ID	See Full Record: nlx_149341
Name	Cell Line Knowledge Base
Additional Info.	Sample type: Cell line, Cell; Availability: Public., The community can contribute to this resource.; Application: Research;
Organism	Human, Mouse, Guinea pig, Rat, Chlorocebus aethiops, Mesocricetus auratus, Channel catfish
Keywords	Cell, Cell line,

Condition
Description	Repository that serves to coordinate searches across data and biospecimen collections from participants in numerous clinical trials and epidemiologic studies and to provide an electronic means for requests for additional information and the submission of requests for collections. The collections, comprising data from more than 80 trials or studies and millions of biospecimens, are available to qualified investigators under specific terms and conditions consistent with the informed consents provided by the individual study participants. Some datasets are presented with studies and supporting materials to facilitate their use in reuse and teaching. Datasets support basic research, clinical studies, observational studies, and demonstrations. Researchers wishing to apply to submit biospecimen collections to the NHLBI Biorepository for sharing with qualified investigators may also use this website to initiate that process.
Type	Biospecimen repository, Data repository, Biomaterial supply resource, Database
NIF ID	See Full Record: nlx_151758
Name	Biologic Specimen and Data Repository Information Coordinating Center
Additional Info.	Availability: Public., The community can contribute to this resource.; Application: Research, Education; Funding: NHLBI;
Organism	Human
Keywords	cardiovascular, pulmonary, hematology, Clinical, clinical trial, Blood, Lung, Heart, Biological specimen, Health, Disease, Medicine, Epidemiology, epidemiologic study

Condition	Pancreatic islet development and function
Description	Consortium to facilitate interdisciplinary collaborations to advance understanding of pancreatic islet development and function. The coordinating center provides access to research databases, reagents and tools. Resources include antibodies, adenoviruses, functional genomics studies, mouse ES cell lines, mouse strains, protocols, etc. Resources are made available to the broader scientific community and submissions are welcome. * BCBC Antibody Collection: The antibody catalog is available not only to BCBC investigators, but to the international research community at large, at various levels of access permissions. The BCBC will produce and maintain a list of available antibodies, and will rate the usefulness of the antibodies requested within the consortium. Antibodies will be made available through an online catalog and order form posted on the website. Custom requests can be made by filling out the 'Request a Custom Antibody' form on the website. * The BCBC Adenovirus Collection is a repository of replication-deficient recombinant adenoviruses. The repository is accessible through this searchable database, created and maintained by the BCBC Coordinating Center, and through which individual viruses may be ordered. Upon request, the user will receive an aliquot of viral stock that may be used for further amplification in HEK293 cells. HEK293 cells are available though the ATCC, or from the investigator's own institutional tissue culture core facility, if available. * Genomics Studies Collection: This collection holds studies that contain information about genes expressed in cells of the pancreas and their transcriptional regulation. Pancreatic genes were also identified by microarray analysis of pancreatic tissues. * The BCBC ESC Line Collection is an information management system that features the collection and dissemination of information on ESC Lines that are useful for beta cell and/or pancreatic development research. The goal of this information resource is to promote sharing these cells in an effort to facilitate collaborations by sharing reagents such as these. * Mouse Collection: The BCBC Mouse Collection provides for the collection and sharing of annotated information on genetically modified mouse strains that are useful for beta cell and/or pancreatic development research. * The BCBC Miscellaneous Resource Collection provides for the collection and sharing of annotated information that is useful for beta cell and/or pancreatic development research. * Protocol Collection: The BCBC Protocol Collection is a resource for the aggregation and dissemination of protocols relevant to beta cell biology. * TRAFEX - TRAnscription Factor EXpression survey is a searchable database of gene expression data.
Type	Database, Community building portal, Data repository, Biospecimen repository, Reagent supplier, Cell repository, Organism supplier, Experimental protocol, Data set
NIF ID	See Full Record: nlx_144143
Name	Beta Cell Biology Consortium
Additional Info.	Sample type: Cell line; Availability: Public: The goal of this information resource is to promote sharing these cells in an effort to facilitate collaborations by sharing reagents such as these., The community can contribute to this resource.; Application: Research; Grant: DK-01-014, DK-01-17, DK-01-18, DK-09-011; Funding: NIDDK;
Organism	Mouse, Non-human animal
Keywords	Pancreatic islet, Diabetes, Mouse, Beta cell, Pancreas, Pancreatic development, Embryonic stem cell, Cell line, Genomics

Condition	retinitis pigmentosa
Description	Supplier of fully penetrant rat models of the retinitis pigmentosa type of inherited retinal degeneration, including the following models: Mutant rhodopsin transgenic rats o P23H mutant rhodopsin transgenic rats -Three lines with different rates of photoreceptor degeneration o S334ter mutant rhodopsin transgenic rats -Five lines with different rates of photoreceptor degeneration RCS (Royal College of Surgeons) rats with inherited retinal dystrophy o RCS pink-eyed inbred strain o RCS pigmented congenic strain with slowed rate of retinal dystrophy o RCS congenic control strains of both pigmentation types, wild-type at the retinal dystrophy (Mertk) genetic locus The resource has been supported by the National Eye Institute (NEI) for the past 19 years to produce and distribute breeding pairs of these animal models to vision scientists. Thus, the following apply: Request for rats requires only a 1-page letter/e-mail addressing 4 questions No charge for the animals or tissues (except for shipping costs) No Material Transfer Agreement (MTA) required No collaboration requirement (in most cases) The resource usually provides multiple breeding pairs of the rats to vision scientists to generate breeding stock. It can also provide extra animals to breed for immediate experimental work, animals of specific ages (depending upon availability), animals with prior exposure to different lighting conditions, eyes taken at specific ages instead of rats for pilot studies and other experiments (fresh, frozen, dissected in specific ways, or fixed with special fixatives or by different methods), or other tissues (e.g., liver, spleen, brain, testis, etc.) prepared different ways.
Type	Organism supplier, Tissue bank
NIF ID	See Full Record: nif-0000-00188
Name	Retinal Degeneration Rat Model Resource
Additional Info.	Sample type: Live rat, Eye, Liver, Spleen, Brain, Testis, etc., Eye tissue, Liver tissue, Spleen tissue, Brain tissue, Testis tissue, Tissue; Availability: Public; Processing: Fresh, Frozen, Dissected, Fixed,; Application: Research; Funding: National Eye Institute, Resource:NIH Blueprint for Neuroscience Research;
Organism	Rat
Keywords	Mutant Rhodopsin transgenic rat, P23H mutant Rhodopsin transgenic rat, S334ter Mutant Rhodopsin transgenic rat, RCS inbred, Congenic strain, Retinitis pigmentosa, Retinal degeneration, Retinal dystrophy, Vision, Rat, Eye, Transgenic rat, Retina, model organism, mutant rat