One Mind: One Voice Bio-repository Cosmic Landscape
Comprehensive global listing of bio-repositories for brain-related diseases, disorders, and conditions.
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Displaying results 1 - 20 out of 465 total results.
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| Condition | |
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| Description | The International Gene Trap Consortium (IGTC) represents all publicly available gene trap cell lines, which are available on a non-collaborative basis for nominal handling fees. International Gene Trap Consortium (IGTC) consists of laboratories around the world working together to generate a public library of mutated murine ES cell lines. Such cell lines can be obtained on a non-collaborative basis by scientists interested in generating reporter-tagged, loss-of-function mutations in mice. In addition to loss of function, newer gene trap vectors offer a variety of post-insertional modification strategies to allow for the generation of other experimental alleles. The cooperative goal of the IGTC is to generate an international resource representing all or most genes in the mouse genome, and to provide the bioinformatics and logistical support to make the resource valuable and available to scientists. Researchers can search and browse the IGTC database for cell lines of interest using accession numbers or IDs, keywords, sequence data, tissue expression profiles and biological pathways. The International Gene Trap Consortium website represents all publicly available gene trap cell lines, which are distributed on a non-collaborative basis for nominal handling fees. By using gene trap cell lines found on the IGTC site, researchers can save the time and expense of targeting a gene for knockout. Researchers can find trapped genes of interest on the IGTC website, and order cell lines for the generation of mutant mice through blastocyst injection. Sponsors: IGTC is supported by grants Funded by NIH grant P41 RR01081-32S2; from the National Institutes of Health. Consortium members include: BayGenomics (USA), Centre for Modelling Human Disease (Toronto, Canada), Embryonic Stem Cell Database (University of Manitoba, Canada), European Conditional Mouse Mutagenesis (European Union), Exchangeable Gene Trap Clones (Kumamoto University, Japan), German Gene Trap Consortium provider (Germany), Sanger Institute Gene Trap Resource (Cambridge, UK), Soriano Lab Gene Trap Resource (Mount Sinai School of Medicine, New York, USA), Texas Institute for Genomic Medicine - TIGM (USA), TIGEM-IRBM Gene Trap (Naples, Italy) Cell line requests are handled by the IGTC members or MMRR Repository, dependent on collection, and users should contact the IGTC member or MMRRC directly with all correspondences regarding cell line distribution. |
| Sample Type | Cell line |
| Processing | |
| Availability | |
| Type | Cell repository, Tissue bank |
| Application | |
| ID | See Full Record |
| Location | Wisconsin International Stem Cell Bank |
| Name | International Gene Trap Consortium |
| Organism | |
| Keywords | Embryo, Embryonic, Gene, Genome, Allele, Analysis, Assay, Bioinformatics, Blastocyst, Cell, Colony, Consortium, Database, Genotyping, Hybridization, In situ, InteRNAtinal, Knock out mouse, Mouse, Murine, Mutant, Mutation, Probe, Qpcr, Researcher, Scientist, Sequence, Stem cell, Tagging, Trap, Vector |
| Condition | All |
|---|---|
| Description | The Coriell Cell Repositories provide essential research reagents to the scientific community by establishing, verifying, maintaining, and distributing cells, cultures and DNA derived from cell cultures. These collections are extensively utilized by research scientists around the world. Scientists can browse the sample catalog and then request specific cell lines for their research studies. An inventory of the remaining stock of each cell line and DNA preparation is presented in real time. Many important research successes have been accomplished using Coriell-managed biospecimens. A prime example is also one of the first: A team of scientists headed by Dr. Nancy Wexler went to Venezuela where an isolated village was found with a high incidence of Huntington's disease. In 1979, cells were brought back to Coriell, cultures established and frozen, and distributed to scientists involved in the search for the Huntington's gene. Five years later, the gene was localized on chromosome 4. In 1994, the gene itself was isolated. From this significant breakthrough, Dr. Wexler and other researchers continue their Huntington's disease research to seek improved treatments. Coriell's significant cell biobank collections include: * NIGMS Human Genetic Call Repository * NINDS Human Genetics DNA and Cell Line Repository * NIA Aging Cell Repository * NHGRI Sample Repository for Human Genetic Research * NEI Age-Related Eye Disease Study (AREDS) Genetic Repository * HD Community BioRepository * American Diabetes Association, GENNID Study * Autism Research Resource Other collections include: * IPBIR Repository * USIDNET Repository * CDC Cell and DNA Repository * Leiomyosarcoma Cell and DNA Repository * Cooperative Huntingtons Observational Trial Repository * YERKES Repository * Human Reference Genetic Material Repository * The Wistar Institute * Human Biological Data Interchange (HBDI) Mouse Embryonic stem cells (mESC) and the NINDS Repository Human Induced Pluripotent Stem Cells (iPSC) are now available. Private repositories are the preferred choice of researchers seeking a flexible, dependable and convenient cold temperature storage solution. Utilizing off-site storage increases your laboratory workspace and secures your samples for both temperature and access, enabling you to make more productive use of your valuable resources. Our repositories are ISO 9000-2001 compliant. |
| Sample Type | Cell line, Culture, Cell, DNA, |
| Processing | |
| Availability | |
| Type | Cell repository, Biomaterial manufacture, Material storage repository, Topical portal, Database, NIF Data Federation |
| Application | |
| ID | See Full Record |
| Location | Coriell Institute for Medical Research |
| Name | Coriell Cell Repositories |
| Organism | |
| Keywords | Cellular, Molecular, Genetics, Reagent, Disease, Family, Gene, Pharmacogenetics, Populations, Single-nucleotide polymorphism |
| Condition | Alzheimer's disease, Late-onset Alzheimer's disease, Dementia, Normal control |
|---|---|
| Description | The goal of the National Cell Repository for Alzheimer's Disease (NCRAD) is to help researchers find genes that increase the risk for Alzheimer's disease (AD) and dementia. To accomplish this goal, in 1990, NCRAD was funded by the National Institute on Aging (NIA) to provide researchers with the biological samples and data necessary for finding important genetic factors in AD and dementia. Understanding the causes of AD and dementia will likely lead to better treatments for this devastating disease. The NIA is committed to determining the causes of AD so that more effective therapies can be developed to treat people with this devastating disorder. To help identify the genes that play a role in the development of AD, the NIA has funded NCRAD as a national resource where clinical information and biological material (DNA, plasma, serum, RNA and brain tissue) can be stored from individuals with AD as well as from individuals without any symptoms of memory loss or dementia. To help identify the genes contributing to the risk for AD, a number of different studies are currently ongoing. These include studies enrolling families with multiple members diagnosed with AD, as well as individuals without a strong family history of AD. NCRAD collects and maintains biological specimens and associated data on large numbers of genetically informative, phenotypically well-characterized families with multiple individuals affected with Alzheimer's disease, as well as individuals for case-control studies. Qualified research scientists may apply to NCRAD for samples and data to conduct genetic research. NIA has in place a Genetics Initiative to assist in the identification of the risk factor genes for Alzheimer's disease. To this end, NIA supports the National Cell Repository for Alzheimer's Disease (NCRAD) at Indiana University as a national repository in order to facilitate access by qualified investigators to samples and Associated Phenotypic Data for the study of the genetics of late-onset Alzheimer's disease. Therefore it is the policy of the NIA that useful specimens and Associated Phenotypic Data for the genetics of late-onset Alzheimer's disease be deposited at NCRAD whenever possible. Qualified investigators will be able to use biological samples and Associated Phenotypic Data supplied by NCRAD. Application for use will be made directly to NCRAD. Associated Phenotypic Data is defined as deidentified data on family structure, age, sex, vital status, psychopathology, diagnosis, and other clinically relevant associated phenotypic information, stripped of all personal identifiers and thus unlinkable to the individuals from whom they were obtained. To help identify the genes contributing to the risk for Alzheimer's disease, a number of different studies are currently ongoing. These include studies enrolling families with multiple members diagnosed with Alzheimer's disease as well as individuals without a strong family history of Alzheimer's disease. The NIA's national effort to help researchers identify the genes that play a role in the development of Alzheimer's disease, seeks to recruit 1,000 families with two or more living brothers or sisters who have been diagnosed with late onset Alzheimer's disease. Through the participation of these families, scientific researchers will be able to obtain the critical information they need to help them identify the genes that increase the risk for late onset Alzheimer's disease. The Alzheimer's Association is working with the National Institute on Aging and study sites across the country to help refer families for this important study. |
| Sample Type | DNA, Plasma, Serum, RNA, Brain tissue, Clinical data, Phenotypic data |
| Processing | |
| Availability | Public: Qualified research scientists may apply to NCRAD for samples and data to conduct genetic research. |
| Type | Tissue bank, Data storage repository, Biomaterial supply resource |
| Application | |
| ID | See Full Record |
| Location | Indiana University; Indiana; USA, US Biobank |
| Name | National Cell Repository for Alzheimers Disease |
| Organism | Human |
| Keywords | Gene, Genetic research, Alzheimer's disease, Clinical, Control, Dementia, DNA, Human, Late onset Alzheimer's disease, Memory loss, Normal, Phenotypic data, |
| Condition | Drug Abuse, Addiction |
|---|---|
| Description | The National Institute of Drug Abuse (NIDA) Human Genetics Initiative is devoted to the collection and distribution of family data from individuals diagnosed with substance abuse disorders for the genetic analysis of drug abuse phenotypes. Anonymous data on family structure, age, sex, clinical status, and diagnosis ("clinical data"), DNA samples and cell line cultures ("biomaterials"), and data derived from genotyping and other genetic analyses of these clinical data and biomaterials ("genetic analysis data"), are distributed to qualified researchers studying the genetics of mental disorders and other complex diseases at recognized biomedical research facilities. Phenotypic and Genetic data will be made available to the general public on the release dates through distribution mechanisms specified on the website. The National Institute on Drug Abuse (NIDA), in collaboration with the National Institutes of Health (NIH), has established the Center for Genetic Studies, under a contract to Rutgers University and its subcontractor, Washington University, to produce, store, and distribute clinical data and biomaterials (DNA samples and cell lines) available in the NIDA Genetics Initiative. Participating studies are as follows: Genetics of Opioid Dependence Mapping of Susceptibility Loci for Nicotine Dependence Molecular Genetics of Heroin Dependence Addictions: Genotypes, Polymorphisms, and Function Genetics of Vulnerability to Nicotine Addiction Family Study of Cocaine Dependence Heroin Dependence Differentiation of Phenotypes for Smoking Pharmacokinetics of Nicotine in Twins Adolescent Drug Dependence Substance Abuse Genetics of Cocaine Induced Psychosis Genome-Wide Analysis for Addiction Susceptibility Genes The Collaborative Genetic Study of Nicotine Dependence Nicotine Dependence Cocaine Dependence Opiate Dependence: Candidate Genes and G x E Effects Genetic Studies of Substance Abuse in Iowa Adoptees Innovative Approaches for Cocaine Pharmacotherapy Twin Family Study of Vulnerability to Substance Abuse Drug Use Substance Use Disorder Liability: Candidate Gene System START (Starting Treatment with Agonist Replacement Therapies) GEDI (The Genes, Environment, and Development Initiative) GEDI (The Genes, Environment, and Development Initiative) Youth Drug Abuse, ADHD and Related Disorders The investigators contact information, release dates, and description of the study are available on the website. |
| Sample Type | DNA, Cell line, Clinical data |
| Processing | |
| Availability | |
| Type | Database, Database, Biomaterial supply resource |
| Application | |
| ID | See Full Record |
| Location | |
| Name | National Institute on Drug Abuse Center for Genetic Studies |
| Organism | Human |
| Keywords | Drug abuse, Family, Family structure, Genetic analysis, Genetics, Addiction, Age, Biomaterial, Cell line, Citation, Clinical, Clinical status, Data resource, Diagnosis, DNA, Genotyping, Human, Mental disorder, Mutation analysis, Phenotypic, Publication, Sex |
| Condition | |
|---|---|
| Description | Mice and rats of varying ages (1-36 months) and genetic backgrounds are available to researchers. NIA maintains colonies of aged rats and mice for use by the scientific community for research directly related to aging and age-related diseases. In addition, NIA supports a tissue bank of flash frozen tissues from mice and rats from the aged rodent colonies and tissue arrays containing punches of multiple ages and multiple tissues per slide. The animals are housed behind specific pathogen-free barriers and monitored for genetic purity and health status, and a health report accompanies each shipment of animals. Available strains: Inbred Rats: Fischer 344 (F344), Brown Norway (BN); Hybrid Rats: F344xBN F1 (F344BN); Inbred Mice: BALB/cBy, CBA, C57BL/6, DBA/2; Hybrid Mice: CB6F1 (BALB/cBy x C57BL/6), B6D2F1 (C57BL/6 x DBA/2); Caloric Restricted Mice: C57BL/6; B6D2F1 |
| Sample Type | |
| Processing | |
| Availability | |
| Type | Organism supplier, Tissue bank |
| Application | |
| ID | See Full Record |
| Location | National Institute on Aging |
| Name | Aging-Related Rodent Colonies |
| Organism | Rodent |
| Keywords | Mouse, Rat, Rodent, Organism bank |
| Condition | |
|---|---|
| Description | Knockout Mouse Project (KOMP) products and services are available from the KOMP Repository. The Repository hosts the vectors, ES cells, mice, embryos, and sperm generated by the NIH KOMP Mutagenesis Project. In addition, the KOMP Repository offers services in support of the KOMP products, including ES cell microinjection, vector cloning, post-insertional modification of cloned ES cells, cryopreservation, assisted reproduction techniques (IVF, ICSI) and mouse breeding, pathology (clinical and anatomical) pathology services, phenotyping services, etc. The KOMP Repository is the final component of a more than $50 million trans-NIH initiative to increase the availability of genetically altered mice and related materials. The University of California, Davis (UC Davis) and Children's Hospital Oakland Research Institute (CHORI) in Oakland, Calif., are collaborating to preserve, protect, and make available about 8,500 types of knockout mice and related products available to the research community. The ??products? are generated by two KOMP mutagenesis teams (the CSD consortium and Regeneron Inc). All KOMP products generated by the CSD consortium and Regeneron are available through the KOMP Repository. Fast, simple, and easy online searching and ordering is available for any KOMP product or service (e.g., microinjection, ICSI for frozen B6 sperm, pathology analysis, etc). If you have made mice from ES cells obtained from the KOMP Repository (such as through the NIH KOMP Supplement Program), then we will gladly accept them into the KOMP Repository. |
| Sample Type | |
| Processing | |
| Availability | |
| Type | Organism supplier, Biomaterial supply resource, Tissue bank, Cell repository, Web accessible database, Biomaterial manufacture, Biomaterial analysis service, Material storage repository |
| Application | |
| ID | See Full Record |
| Location | University of California at Davis; California; USA |
| Name | Knockout Mouse Project Repository |
| Organism | Knock out mouse |
| Keywords | Embrynomic, Embryo, Gene, Breeding, Cell, Cryopreservation, Deletion, Genotyping, Germplasm, Knock out mouse, Microinjection, Mouse, Mutagenesis, Mutation, Null, Repository, Stem, Vector, Reanimation |
| Condition | Bipolar Disorder, Schizophrenia, Alzheimer's disease, Autism, Attention deficit-hyperactivity disorder, Depression, Control, Obsessive-Compulsive Disorder, Anorexia Nervosa, Relative, Mental disorder, Brain disorder, Relative, |
|---|---|
| Description | The Center for Collaborative Genomic Studies on Mental Disorders produces, stores, and distributes clinical data and biomaterials (DNA samples and cell lines) available in the NIMH Human Genetics Initiative. The Center creates and distributes computational tools that support investigation and analysis of the clinical data. In addition, the Center creates tools that enables researchers to determine which samples or data might be of use to them, so that they may request access from NIMH.
The goal of this Initiative is to study individuals affected with schizophrenia, bipolar disorder, or Alzheimer's disease and their relatives, in order to establish a national resource of clinical/diagnostic information and immortalized cell lines for DNA extraction. These data and biomaterials are distributed to qualified investigators in the wider scientific community, for use in research on the genetic basis of these disorders.
Data is available from diagnostic and family interviews for genetic studies: Diagnostic Interview for Genetic Studies (DIGS); and Family Interview for Genetic Studies (FIGS). CGSMD Data Explorer provides a web interface for easy access to the back-end CGSMD data warehouse. The CGSMD data warehouse stores all the files available through nimhgenetics.org website into tables. These files are available in various formats, and are using different notations. They were converted to a specific format, curated and loaded into tables, with a domain model constructed on top of the tables to harmonize the values. The Data Explorer is a web-based tool that provides access to this curated, harmonized, back-end data warehouse. |
| Sample Type | DNA, Cell line, |
| Processing | |
| Availability | Public:Data and biomaterials are distributed to qualified investigators in the wider scientific community, for use in research on the genetic basis of these disorders. |
| Type | Biomaterial supply resource, Cell repository, Data set, Biomaterial manufacture, Data analysis service |
| Application | Research |
| ID | See Full Record |
| Location | Rutgers University; New Jersey; USA, Washington University in St. Louis; Missouri; USA, University of Southern California; California; USA, US Biobank Address:Washington University School of Medicine, Department of Psychiatry, 660 South Euclid Avenue, Campus Box 8134, Saint Louis, MO 63110-1093 Fax: 314-286-2577 |
| Name | NIMH Center for Collaborative Genetic Studies on Mental Disorders |
| Organism | Human |
| Keywords | DNA, Cell line, Clinical data, Mental disorder, Mental functioning, Bipolar Disorder, Schizophrenia, Alzheimer's disease, Autism, Attention deficit-hyperactivity disorder, Depression, Control, Obsessive-Compulsive Disorder, Anorexia Nervosa, Brain disorder, Relative, GWAS Data, Sequence Data, CATIE, STAR*D, STEP-BD, ACLAIM, EMBARC, Psychiatric GWAS Consortium, Family Interview for Genetics Studies, Diagnostic Interview for Genetic Studies, Single-nucleotide polymorphism |
| Condition | Aged, Alzheimer's disease, Progeria, Parkinson's disease, Werner syndrome, Cockayne syndrome, Obesity, Premature aging disorder, Premature aging, Normal control, Late adult human, Adolescent, |
|---|---|
| Description | The AGING CELL REPOSITORY is a resource facilitating cellular and molecular research studies on the mechanisms of aging and the degenerative processes associated with it. The cells in this resource have been collected over the past three decades using strict diagnostic criteria and banked under the highest quality standards of cell culture. Scientists use the highly-characterized, viable, and contaminant-free cell cultures from this collection for research on such diseases as Alzheimer disease, progeria, Parkinsonism, Werner syndrome, and Cockayne syndrome. The collections of the Repository include DNA and cell cultures from individuals with premature aging disorders such as progeria and Werner syndrome as well as Alzheimer Disease and Parkinsonism. The collection includes DNA from individuals of great age from the the Baltimore Longitudinal Study of Aging at the Gerontology Research Center as well as other Longevity Collections including the Aged Sib Pair Collection. The Repository also includes samples from an Adolescent Study of Obesity, Apparently Healthy Controls, Animal Models of Aging and both human and animal differentiated cell types. Scientists can use the highly-characterized, viable, and contaminant-free cell cultures from this collection for genetic and cell biology research. |
| Sample Type | DNA, Cell culture, Stem cell, Embryonic stem cell, Fibroblast, Adipose stromal cell, Cell |
| Processing | |
| Availability | Public |
| Type | Cell repository, Database, Material storage repository |
| Application | Research |
| ID | See Full Record |
| Location | Coriell Cell Repositories, US Biobank |
| Name | Aging Cell Repository |
| Organism | Human, Mouse, Non-human animal |
| Keywords | DNA, Aging, Cell, Disorder, Obesity, Aged, Alzheimer's disease, Progeria, Parkinson's disease, Werner syndrome, Cockayne syndrome, Premature aging disorder, Premature aging, Cell culture, Healthy control, Late adult human, Adolescent, Embryonic stem cell, Stem cell, Fibroblast, Adipose stromal cell, Ames dwarf mouse, Gerontology |
| Condition | Huntington's disease, Parkinson's disease, Healthy, Mental disease, Neurological disorder, Normal control, Alzheimer's disease, Schizophrenia, Bipolar Disorder, Relative, Parent, Sibling, Child, Lewy Body Variant Alzheimer's disease, Amyotrophic Lateral Sclerosis, Dementia, Unipolar Depressive Dissorder, Diffuse Lewy Body Disease, DYT-1 Dystonia, Progressive Supranuclear Palsy, Rett Syndrome, Tourette's Syndrome, |
|---|---|
| Description | The Harvard Brain Tissue Resource Center has been established at McLean Hospital as a centralized resource for the collection and distribution of human brain specimens for brain research. This is a national resource for the acquisition, processing, storage, distribution of high quality postmortem brain specimens for brain research. Specimens are obtained at no charge via a request form downloaded at website. Research over the past decade has shown that the study of human brain tissue is essential to increasing our understanding of how the nervous system functions. Most recently, postmortem human brain research has played a significant role in the development of a genetic test for Huntington's disease as well as a treatment for Parkinson's disease. Similarly, neurochemical and anatomical studies focusing on the biological nature of the severe mental illnesses are now emerging and bringing forth new hope for understanding the underlying brain mechanisms responsible for psychosis and other symptoms associated with these debilitating brain disorders. In order to perform research into the neurological or psychiatric disorders, it is vital to collect normal control tissue as well. Scientists from the nation's top research and medical centers request tissue from The Brain Bank for their investigations. Since the majority of these studies can be carried out on a very small amount of tissue, each donated brain provides a large number of samples for many researchers. However, in order to conduct valid experiments, it is necessary to supply researchers with a variety of brain specimens. Various types of brain tissue are collected including those with neurological and psychiatric disorders, and their parents, siblings and offspring. The HBTRC maintains the most extensive collection of postmortem human brains from individuals with Huntington's chorea, Alzheimer's disease, Parkinson's disease, and a growing number of other neurological disorders. In addition, the HBTRC also has a significant collection of brains from individuals diagnosed with schizophrenia and manic depressive illness, as well as "normal-control" specimens that are essential as a comparison group for all of these brain disorders. The Brain Tissue Resource Center is interested in collecting tissue from individuals diagnosed with various other disorders not mentioned. With the NIH funding that supports the HBTRC, all disbursements are made at no cost to the recipient laboratory. See the National Brain Databank below for gene expression data related to samples. |
| Sample Type | Brain tissue, Brain, Tissue, Cerebral Spinal Fluid |
| Processing | Fresh quick-frozen, Block, Coronal section, Nitrogen vapor frozen, Dry ice frozen, Passive frozen, Formalin-fixed, Frozen |
| Availability | Public: Scientists from the nation's top research and medical centers request tissue from The Brain Bank for their investigations. |
| Type | Brain bank, Tissue bank, Material storage repository, |
| Application | Research |
| ID | See Full Record |
| Location | Harvard Medical School; Massachusetts; USA, McLean Hospital; Massachusetts; USA, US Biobank Address:Harvard Brain Tissue Resource Center, McLean Hospital, 115 Mill Street, Belmont, MA 02478 Telephone:1-800-BRAIN-BANK (1-800-272-4622) Fax: (617) 855-3199 |
| Name | Harvard Brain Tissue Resource Center |
| Organism | Human |
| Keywords | Brain tissue, Brain, Tissue, Cerebral Spinal Fluid, Fresh quick-frozen, Block, Coronal section, Nitrogen vapor frozen, Dry ice frozen, Passive frozen, Formalin-fixed, Frozen, Huntington's disease, Parkinson's disease, Healthy, Mental disease, Neurological disorder, Normal control, Alzheimer's disease, Schizophrenia, Bipolar Disorder, Relative, Parent, Sibling, Child, Lewy Body Variant Alzheimer's disease, Amyotrophic Lateral Sclerosis, Dementia, Unipolar Depressive Dissorder, Diffuse Lewy Body Disease, DYT-1 Dystonia, Progressive Supranuclear Palsy, Rett Syndrome, Tourette's Syndrome, Restless Legs Syndrome, Autism, Post-mortem, Late adult human, Data set, Gene expression |
| Condition | Human immunodeficiency virus, Neurocognitive disease, Normal, Subsyndromic, Minor Cognitive Motor Disorder, HIV - Associated Dementia, Cytomegalovirus Encephalitis, Neurological impairment, |
|---|---|
| Description | The National NeuroAIDS Tissue Consortium (NNTC), supported by NIMH and NINDS funding, was established in 1998 to collect, store, and distribute samples of nervous tissue, cerebrospinal fluid, blood, and other tissue from HIV-infected individuals. The NNTC mission is to bolster research on the effects of HIV infection on human brain by providing high-quality, well-characterized tissue samples from patients who died with HIV, and for whom comprehensive neuromedical and neuropsychiatric data were gathered antemortem. Researchers can request tissues from patients who have been characterized by: * degree of neurobehavioral impairment * neurological and other clinical diagnoses * history of drug use * antiretroviral treatments * blood and CSF viral load * neuropathological diagnosis The NNTC encourages external researchers to submit tissue requests for ancillary studies. The Specimen Query Tool is a web-based utility that allows researchers to quickly sort and identify appropriate NNTC specimens to support their research projects. The results generated by the tool reflect the inventory at a previous time. Actual availability at the local repositories may vary as specimens are added or distributed to other investigators. |
| Sample Type | Tissue, Plasma, Peripheral Blood Mononuclear Cell, Serum, Urine, Spinal Cord, Nervous tissue, Pituitary Gland, Trigeminal Ganglia, Dorsal Root Ganglia, Peripheral Nerve, Lymph Node, Liver, Spleen, Adipose tissue, Bone Marrow, Muscle, Hair, Heart, Thymus, Kidney, Lung, Eye, Brain, |
| Processing | Frozen, Fixed |
| Availability | Public: The NNTC encourages external researchers to submit tissue requests for ancillary studies. |
| Type | Tissue bank, Biomaterial supply resource, Data set, Brain bank |
| Application | Research |
| ID | See Full Record |
| Location | National Institute of Mental Health, US Biobank Address:NNTC Data Coordinating Center, The EMMES Corporation, 401 North Washington St. Suite 700, Rockville, MD 20850 Phone: 301-251-1161 Toll-free:1-866-668-2272 Fax:301-576-4597 |
| Name | National NeuroAIDS Tissue Consortium |
| Organism | Human |
| Keywords | Human immunodeficiency virus, Nervous tissue, Cerebral Spinal Fluid, Blood, Tissue, Brain, Neuromedical data, Neuropsychiatric data, Fixed brain, Frozen brain, Ante-mortem Cerebral Spinal Fluid, Post-mortem Cerebral Spinal Fluid, Tissue, Plasma, Peripheral Blood Mononuclear Cell, Serum, Urine, Spinal Cord, Nervous tissue, Pituitary Gland, Trigeminal Ganglia, Dorsal Root Ganglia, Peripheral Nerve, Lymph Node, Liver, Spleen, Adipose tissue, Bone Marrow, Muscle, Hair, Heart, Thymus, Kidney, Lung, Eye, Brain, Ante-mortem, Post-mortem, Normal, Subsyndromic, Minor Cognitive Motor Disorder, HIV - Associated Dementia, Cytomegalovirus Encephalitis, Neurological impairment, Traumatic Brain Injury, Neurocognitive disease, Frozen, Fixed, AIDS, One Mind TBI, Asymptomatic Neurocognitive Impairment, Minor Cognitive Disorder, Gene Array, SNP |
| Condition | Aged |
|---|---|
| Description | Tissues are available as fresh frozen (stored at -80 degrees Celsius), fixed blocks, slides from fixed blocks, fresh frozen in OCT medium (on a limited basis)Tissue from NIA's Nonhuman Primate Tissue Bank is available to investigators at academic and nonprofit research institutions who are engaged in funded research on aging. The project name and funding source must accompany all orders. It may not be possible to ship tissue to countries that have restrictions on the import of animal tissues or products. Investigators at for-profit entities are not eligible to purchase tissue from NIA's Nonhuman Primate Tissue Bank unless it is for a Small Business Innovation Research grant from NIA. This tissue bank is a repository of tissue from aged non-human primates (NHP) for use in research. Some tissue from middle-aged and young NHP will also be available soon. The tissues are donated by NIA-supported NHP colonies and other NHP colonies such as the National Primate Research Centers. |
| Sample Type | |
| Processing | |
| Availability | |
| Type | Tissue bank |
| Application | |
| ID | See Full Record |
| Location | National Institute on Aging,National Institutes of Health |
| Name | Aged Nonhuman Primate Tissue Bank |
| Organism | Non-human primate |
| Keywords |
| Condition | All |
|---|---|
| Description | The goal of the Mammalian Gene Collection (MGC), a trans-NIH initiative, is to provide full-length open reading frame (FL-ORF) clones for human, mouse, and rat genes. In 2005, the project added the cow cDNAs generated by Genome Canada. MGC cDNA clones were obtained by screening of cDNA libraries, by transcript-specific RT-PCR cloning, and by DNA synthesis of cDNA inserts. All MGC sequences are deposited in GenBank and the clones can be purchased from distributors of the IMAGE consortium. You can use Download Plugin Adobe Acrobat Reader "A Guide to Finding Mammalian Gene Collection (MGC) Clones and Evaluating Their Sequence" to assist in determining whether MGC cDNA clones for human, mouse, or rat genes and transcripts of interest are available for purchase or sequence investigation. ORFeome Collaboration (OC) was formed to provide the research community with sequence-validated, full-ORF human cDNA clones in the Gateway vector format. * Total MGC full ORF clones: Human 29,818; Mouse 27,285; Rat 6,763; Bovine 9,104 * Non-redundant genes: Human 17,592; Mouse 17,701; Rat 6,486; Bovine 8,724 With the conclusion of the MGC project in March 2009, the GenBank records of MGC sequences will be frozen, without further updates. Since the definition of what constitutes a full-length coding region for some of the genes and transcripts for which we have MGC clones will likely change in the future, users planning to order MGC clones will need to monitor for these changes. Users can make use of genome browsers and gene-specific databases, such as the UCSC Genome browser, NCBI?s Map Viewer, and Entrez Gene, to view the relevant regions of the genome (browsers) or gene-related information (Entrez Gene) |
| Sample Type | Cell line, cDNA |
| Processing | Frozen |
| Availability | Public: The goal of the Mammalian Gene Collection (MGC), a trans-NIH initiative, is to provide researchers with unrestricted access to sequence-validated full-length protein-coding (FL-CDS) cDNA clones for human, mouse, and rat genes. In 2005, the project added the cow cDNAs generated by Genome Canada. |
| Type | Cell repository |
| Application | Research |
| ID | See Full Record |
| Location | National Cancer Institute, US Biobank |
| Name | Mammalian Gene Collection |
| Organism | Human, Mouse, Rat, Bos taurus |
| Keywords | Cell line, cDNA, Frozen, Clone, Vector, Gene, Open reading frame |
| Condition | Alzheimer's disease, Normal, Neurological disorder, Dementia with Lewy bodies, Alcohol-related Dementia, Dementia Primary Progressive Aphasia, Progressive Supranuclear Palsy, Corticobasal Degeneration, Huntington's disease, Prion Disease, Cognitive Dysfunction from medication, Cognitive Dysfunction from Medical Illnesses, Depression, Mental disease, Down's syndrome, Parkinson's disease, Stroke, Hydrocephalus, Brain Injury, Central nervous system neoplasm, Control subject |
|---|---|
| Description | The National Alzheimer's Coordinating Center was established in 1999 to facilitate collaborative research. Using data collected from the 29 NIA-funded Alzheimer's Disease Centers (ADCs) across the United States, NACC has developed and maintains a large relational database of standardized clinical and neuropathological research data. In partnership with the Alzheimer's Disease Genetics Consortium (ADGC) and the National Cell Repository for Alzheimer's Disease (NCRAD), NACC provides a valuable resource for both exploratory and explanatory Alzheimer's disease research. NACC data are freely available to all researchers. NACC will provide help to researchers locating specific classes of specimens and direct them to the individual ADCs, where they may request access to stored specimens. NACC developed and maintains a large relational database of standardized clinical and neuropathological research data collected from each ADC, and this database provides a valuable resource for both exploratory and explanatory Alzheimer's disease research. Data are submitted continuously by the participating ADC but are frozen and certified app An account is NOT necessary to download UDS data collection forms and documentation or to request data from NACC. Any researcher, whether affiliated with an ADC or not may request a data file for analysis or aggregate data tables. Aggregate data tables requested are produced and returned as soon as the queue allows (usually within 1-3 days depending on the complexity). Data file requests, for the researchers own analysis, require a brief. 1-2 page description of the intended research and usually some initial consultation with a NACC analyst to ensure that the data elements to be included in the file are adequate to address the research question. The data provided are HIPAA de-identified. The database consists of several datasets, and searches may be done on the entire database or on individual datasets. Access is granted by security level. The Minimum Data Set (MDS) - Brief, cross-sectional clinical and demographic data abstracted for subjects enrolled in NIA Alzheimer's Disease Centers 1984 - 2005. The Uniform Data Set (UDS) - Standardized clinical examination, testing, diagnostic evaluation and data collection protocol with annual longitudinal follow-up. Implemented September 2005 and continuing. Approximately 20,000 subjects have been enrolled in the UDS as of July, 2010. * Neuropathology Data Set (NP) - Neuropathologic features of subjects who had post-mortem neuropathological examination, 1984 - present. These data include those subjects with MDS and/or UDS clinical data. NACC Tissue Location Request- Basic data on all patients enrolled in NIA-funded ADCs since they were established in 1984 have been collected at NACC (established in 1999). There are more than 70,000 subjects enrolled in the ADCs; some of them have provided biological specimens (e.g., brain, CSF, blood, DNA). These specimens were collected under various protocols (depending on the research needs of scientists locally) and are stored at the individual ADCs. A tabulation of the specimens by primary neuropathological diagnosis existing collectively at the ADCs is shown below. NACC will provide help to researchers locating specific classes of specimens and direct them to the individual ADCs, where they may request access to stored specimens. |
| Sample Type | Brain, CSF, Blood, DNA, Clinical data, Neuropathological data, |
| Processing | Frozen |
| Availability | Public: NACC data are freely available to all researchers. |
| Type | Biomaterial supply resource, Topical portal, Data set |
| Application | Research |
| ID | See Full Record |
| Location | University of Washington; Washington; USA, US Biobank |
| Name | National Alzheimers Coordinating Center |
| Organism | Human |
| Keywords | Alzheimer's disease, Brain, Clinical, Data resource, Disease, Human, Late adult human, Neuropathological, Neuropathology, Specimen, Tissue |
| Condition | Aged |
|---|---|
| Description | NIA aged rodent tissue arrays offer high-throughput analysis of tissue histology and protein expression for the biogerontology research community. Each array includes tissue cores from multiple tissues at multiple ages on one slide. The arrays are made from ethanol-fixed tissue and can be used for all techniques for which conventional tissue sections can be used. Ages are chosen to span the life from young adult to very old age. Images of H&E stained punches are available for Liver, Cardiac Muscle, and Brain. The NIA aged rodent tissue arrays were developed with assistance from the National Cancer Institute (NCI) Tissue Array Research Program (TARP), led by Dr. Stephen Hewitt, Director. NCI TARP contains more information on tissue array construction, protocols for using arrays, and references. Preparation and Product Description Tissue arrays are prepared in parallel from different sets of animals so that experiments can be conducted in duplicate, with each array using unique animals with a unique product number. The product descriptions page describes each array, including: Strain Gender Ages Tissues Animal Identification Numbers The product descriptions page also provides links to the animal vital statistics documents and array layout diagram. NIA aged rodent tissue arrays are available to investigators at academic and nonprofit research institutions that are engaged in projects directly related to aging and age-related disorders. |
| Sample Type | |
| Processing | |
| Availability | |
| Type | Tissue bank |
| Application | |
| ID | See Full Record |
| Location | National Institute on Aging |
| Name | Aged Rodent Tissue Arrays |
| Organism | Rodent |
| Keywords | f344 x bn f1 hybrid rat, Aged, Biogerontology, Brain, C57BL/6, Caloric rESTricted, Heart, Kidney, Liver, Lung, Mouse, Muscle, Old, Pancreas, Prostate, Protein expression, Rodent, Skin, Spleen, TESTes, Tissue array, Tissue core, Tissue histology, White adipose tissue, Early adult |
| Condition | Developmental disorder, Down's syndrome, Chromosomal defect, Mitochondrial encephalopathy, Phenylketonuria, Maternal PKU, Rett Syndrome, Dyslexia, Autism, Neurodevelopmental disorder, Aminoacidopathy, Pervasive Development Disorder, Leukodystrophy, Lysosomal disorder, S syndrome, |
|---|---|
| Description | The objective of this human tissue repository is to systematically collect, store, and distribute brain and other tissues for research dedicated to the improved understanding, care, and treatment of individuals with developmental disorders. Of special interest are individuals with Down's syndrome and other chromosomal defects, mitochondrial encephalopathies, phenylketonuria and other aminoacidopathies, maternal PKU, Rett syndrome, leukodystrophies, lysosomal disorders, dyslexia, autism, and other neurodevelopmental disorders. The BRAIN AND TISSUE BANKS have extensive experience in arranging for the rapid retrieval of tissue upon the death of individuals who die while at home, in hospitals or hospice care. As a special service, the BRAIN AND TISSUE BANKS are able to assist researchers who are working with patients who intend to donate tissues at the time of their death. Immediately after retrieval of the tissue, the BRAIN AND TISSUE BANKS will forward needed tissue to the referring investigators and ensure proper storage and cataloging of any additional tissues as part of the BRAIN AND TISSUE BANKS. The recipient of tissue and the BRAIN AND TISSUE BANK are required to sign a Tissue Transfer Agreement before any tissues are transferred. Tissues are made available to academic researchers and commercial enterprises for basic research. All requests for tissue must be submitted online. If feasible, the NICHD BTB will prospectively collect additional tissues and process it according to a researcher's specifications. Brain sections are primarily frozen in isopentane / dry ice. Tissues are stored in 10% formalin and frozen at -85 degrees C. |
| Sample Type | Tissue, Brain, Body fluid, Cardiovascular system, Endocrine system, Genital system, Gastrointestinal system,Hematopoietic system, Integumentary, Musculo-Skeletal, Respiratory system, Spinal cord, Nerve, Urinary system, Other, RNA |
| Processing | Frozen, Fixed |
| Availability | Public: Tissues are made available to academic researchers and commercial enterprises for basic research. |
| Type | Tissue bank, Material storage repository, Brain bank, Biomaterial supply resource |
| Application | Research |
| ID | See Full Record |
| Location | University of Maryland School of Medicine; Maryland; USA, US Biobank Address:NICHD BRAIN AND TISSUE BANK, University of Maryland School of Medicine, Department of Pediatrics, 655 W. Baltimore Street, 13-013 BRB, Baltimore, MD 21201-1559 Telephone:(410) 706-1755 (800) 847-1539 Fax: 410-706-2128 |
| Name | NICHD Brain and Tissue Bank for Developmental Disorders |
| Organism | Human |
| Keywords | Downloadable catalog, Tissue, Brain, Body fluid, Cardiovascular system, Endocrine system, Genital system, Gastrointestinal system, Hematopoietic system, Integumentary, Musculo-Skeletal, Respiratory system, Spinal cord, Nerve, Urinary system, Other, RNA, Frozen, Fixed, Developmental disorder, Down's syndrome, Chromosomal defect, Mitochondrial encephalopathy, Phenylketonuria, Maternal PKU, Rett Syndrome, Dyslexia, Autism, Neurodevelopmental disorder, Aminoacidopathy, Pervasive Development Disorder, Leukodystrophy, Lysosomal disorder, S syndrome, |
| Condition | |
|---|---|
| Description | The Xenopus Gene Collection (XGC) is an NIH initiative that supported the production of cDNA libraries, clones and 5'/3' sequences to provide a set of full-length (open reading frame) sequences and cDNA clones of expressed genes for Xenopus laevis and Xenopus tropicalis. The distribution of clones is outsourced to several for profit companies, links are available. The project concluded in September 2008, and all resources generated by the XGC are publicly accessible to the biomedical research community. The genomic resources available to the Xenopus laevis and Xenopus tropicalis community include the following components: The generation of libraries from different stages of development and adult tissues. Sequencing of ~3,000 to 10,000 5' and 3' ESTs from each library. All sequences are deposited into GenBank. The corresponding clones are available through the IMAGE clone distribution network and are fully accessible to the community. Analysis of all available sequences into UniGene clusters. Selection of candidate complete open reading frame (ORF) clones and their sequencing. With the conclusion of the XGC project, the GenBank records of XGC sequences will be frozen, without further updates. Since the knowledge of what constitutes a full-length coding region for some of the genes and transcripts for which we have XGC clones will likely change in the future, users planning to order XGC clones will need to monitor for these changes. Users can make use of genome browsers and gene-specific databases, such as the UCSC Genome browser, NCBI's Map Viewer, and Entrez Gene, to view the relevant regions of the genome (browsers) or gene-related information (Entrez Gene). |
| Sample Type | |
| Processing | |
| Availability | |
| Type | Tissue bank, Database |
| Application | |
| ID | See Full Record |
| Location | National Institutes of Health |
| Name | Xenopus Gene Collection |
| Organism | Xenopus laevis, Xenopus tropicalis, Xenopus |
| Keywords | EST sequencing, Expressed genes, Frog, Gene, Adult, CDNA, CDNA library, Clone, Genomic, Open reading frame, Sequencing, Stage, Tag, Vector, |
| Condition | Autism, Autism spectrum disorder, Pervasive Development Disorder |
|---|---|
| Description | The Autism Genetic Resource Exchange (AGRE) is a program of Autism Speaks to advance genetic research in autism spectrum disorders. Genetic biomaterials and clinical data are obtained from families that have more than one family member diagnosed with an Autism Spectrum Disorder. The biological samples, along with the accompanying clinical data, are made available to AGRE-approved researchers. AGRE is a DNA repository and family registry, housing a database of genotypic and phenotypic information that is available to autism researchers worldwide. As they become available, additional family pedigrees will be posted on our online catalog which, based on the expanding nature of the resource, provides the most up-to-date availability of pedigrees and biomaterials. Cell lines have been established for the majority of families in this collection and serum/plasma is available on a subset of the subjects until stocks are depleted. The diagnosis of autism has been made using the standard Autism Diagnostic Interview-Revised (ADI-R) algorithm. In addition, AGRE provides two other diagnostic classifications (Not Quite Autism and Broad Spectrum) to characterize those individuals on the broader autism spectrum who do not meet full ADI-R criteria. ADI-R information and pedigree configurations are available for all families in our collection. Ethnicity data have been collected on 933 of the 1000 families and further data continue to be gathered. Autism Diagnostic Observation Schedule (ADOS) evaluations are currently available for 789 families. Detailed birth and medical histories, physical and neurological examinations (including basic dysmorphology assessments), as well as family and medical information for parents and unaffected siblings, are available for 358 families. These data continue to be collected for the remainder of the catalog families. We have prioritized karyotyping for those families with suspected chromosome 15 duplications. To date, 522 families have been karyotyped, 187 analyzed for SNRPN duplications at 15q12, and 367 for telomere analyses for small-scale deletions and duplications by Dr. Christa Lese Martins laboratory at Emory University. These data are posted on the registered and password-protected portion of the AGRE researcher website. To obtain access to the AGRE collection, researchers must receive approval from the AGRE Steering Committee by completing the Researcher Access application and the signing of the Researcher Distribution Agreement found on the AGRE website. A copy of the researchers current IRB approval or exemption must accompany their application. When an application is approved, a username and password will be issued by the AGRE Researcher Liaison that will allow the researcher to access the Approved Researchers section of the website. Biomaterial orders are processed by the AGRE Researcher Liaison in the Los Angeles office. DNA and clinical information are made available to AGRE-approved researchers for analysis. |
| Sample Type | DNA, Cell line, Serum, Plasma |
| Processing | Frozen |
| Availability | Public: The biological samples, along with the accompanying clinical data, are made available to AGRE-approved researchers worldwide. |
| Type | Database, Biomaterial supply resource, Material storage repository, Data storage repository |
| Application | Research |
| ID | See Full Record |
| Location | Autism Speaks, US Biobank Address:Autism Genetic Resource Exchange, Autism Speaks, 5455 Wilshire Blvd., Suite 2250, Los Angeles, CA 90036-4234 FAX: 323-931-1977 |
| Name | Autism Genetic Resource Exchange |
| Organism | Human |
| Keywords | Phenotyping, Evaluation, Family registry, Gene bank, Genetic biomaterial, Genetics, Autism Diagnostic Interview ? Revised, Autism Diagnostic Observational Scales, Assessment, Autism, Autism diagnostic observation schedule, Autism spectrum disorder, Birth, Clinical data, Genetic data, Diagnoses, Genome scan, Genotypic data, Medical history, Pedigree, Phenotypic data, DNA, Cell line, Serum, Plasma, Biorepository, Biospecimen, Pervasive Development Disorder, Phenotype, Frozen |
| Condition | Ophthalmic disease |
|---|---|
| Description | While there is no public data available here, the Network provides access to patient samples coupled to anonymous phenotypic data for CLIA (select eye disease laboratories). The Network includes a coordinating center, a centralized repository for blood/DNA/cell lines, several CLIA laboratories and a shared genotype / phenotype database. The goal of the NEI is to augment, not diminish, existing university-based and commercial ventures, while providing a new entry portal with rapid, reliable, and easy access to medical professionals. Over the past 15 years, nearly 500 genes that contribute to inherited eye diseases have been identified. Disease-causing mutations are associated with many ocular diseases, including glaucoma, cataracts, strabismus, corneal dystrophies and a number of forms of retinal degenerations. This remarkable new genetic information highlights the significant inroads that are being made in understanding the medical basis of human ophthalmic diseases. As a result, gene-based therapies are actively being pursued to ameliorate ophthalmic genetic diseases that were once considered untreatable. The ability to detect disease-causing mutations in many individuals with inherited ophthalmic diseases offers significant benefits for patients and their families. It is now possible to provide genetic testing for patients diagnosed with ocular diseases by screening for these genes. This remarkable opportunity, however, has now created the challenge of providing genetic information to individuals who want to know whether they could benefit from the treatments that are being developed. Unfortunately, this type of DNA testing is not widely available. The National Eye Institute is working with a number of vision research laboratories to make this testing more readily available to patients and their families. These laboratories will collect and maintain relevant information in secure databases that will be available to researchers to help speed the progress toward developing treatments and also help identify those who are most likely to benefit from them. The Search for Answers The National Eye Institute (NEI) hosted a meeting on November 10, 2003, to discuss the possible formation of a national collaborative network for ophthalmic research and diagnostic genotyping. Attendees included expert ophthalmic geneticists from the United States, Canada and England, as well as experts in genetic counseling, bioethics, federal regulatory requirements, and representatives from non-profit organizations interested in rare genetic diseases. The meeting participants reached the consensus that a coordinated effort could and should be made to establish a community resource for ophthalmic genetic disease. This resource would include patient access to diagnostic genotyping, genetic counseling and information services, a patient database that would be shared among researchers, and a genetic specimen repository. The participants predicted that this resource would benefit patients by providing medically useful information and at the same help to speed research into treatments for these conditions. The Outcome The NEI is working with the vision community to initiate an eyeGENETM - National Ophthalmic Disease Genotyping Network. The NEI is committed to facilitate access to already existing CLIA-certified research laboratories within the vision community, as well as aid in the support of establishing additional CLIA-certified laboratories. The Network will assist in developing public and professional awareness of genotype / phenotype resources that are available to people with various ocular genetic diseases, their clinicians, and scientists studying these diseases. The Network will enhance recruitment of patients interested in participating in future clinical trials related to genetic eye diseases. Because the eyeGENETM program will be a national resource, patients will have greater access to diagnostic gene testing and genetic information. Clinicians and researchers will have access to: diagnostic genetic testing; centralized specimen collection, processing, and repository services, standardized phenotypic descriptors; and a shared database of genotype/phenotype information. This will allow the analysis of larger datasets that are necessary to identify novel genetic risk factors for ocular diseases, and answer pharmaco-genetic and epidemiologic questions of ocular disease. |
| Sample Type | |
| Processing | |
| Availability | |
| Type | Tissue bank |
| Application | |
| ID | See Full Record |
| Location | National Eye Institute |
| Name | National Ophthalmic Disease Genotyping Network (eyeGENETM) |
| Organism | |
| Keywords | Familial exudative vitreal retinopathy fzd4, Foxc1, Abca4, Aniridia pax6, Axenfeld - rieger syndrome pitx2, BEST's disease vmd2, Bietti's crystalline corneal-retinal dystrophy cyp4v2, C1qtnf5/ ctrp5, Ca4, Choroideremia chm, Cnga1, Cone rod dystrophy abca4, Congenital cranial dysinnervation diseases (ccdd) kif21a, Congenital stationary night blindness nyx, Corneal anterior stromal dystrophies bigh3, Crb1, Doyne honeycomb dystrophy efemp1, Glaucoma cyp1b1, Hoxa1, Impdh1, Juvenile x-linked retinoschisis xlrs1, Krt12, Lrp5, Meesman's epithelial dystrophy krt3, Mertk, Myoc, Ndp, Optic atrophy opa1, Optn, Pantothenate kinase-associated neuropathy (pkan) pank2, Pattern dystrophy rds, Pde6a, Pde6b, Phox2a, Prpf31, Retinitis pigmentosa (rp) and retinal degenerations abca4, Rgr, Rho, Rlbp1, Robo3, Rp1, Rp2, Rpe65, Rpgr, Sall4, Sorsby fundus dystrophy timp3, Stargardt disease elovl4, Tulp1 |
| Condition | Neurodegenerative disease, Mental disease, Neurological disorder |
|---|---|
| Description | The Human Brain and Spinal Fluid Resource Center was established in 1961 to provide a vital service to neuroscientists. The Center collects, stores, and distributes donated tissue to research scientists around the world. Collection occurs through our ??Gift of Hope? anatomical donor program which accepts tissue donation from people with neurological/ psychiatric disorders. By arranging to donate tissue after death, you are giving a priceless gift to humanity. The Center also provides a continuous boost to biomedical research by helping scientists help patients. It provides researchers with the higheset quality and quantity of pre- and post-mortem brains, spinal cords, cerebrospinal fluid (CSF), serum, blood cells and urine to use in their investigations of neurological and psychiatric diseases. By applying a wide variety of standardized research methods, scientists can test their hypotheses utilizing the specimens provided by the Center. |
| Sample Type | Tissue, Brain, Spinal cord, Cerebral Spinal Fluid, Serum, Blood cell, Urine |
| Processing | |
| Availability | Public: The Center collects, stores, and distributes donated tissue to research scientists around the world. |
| Type | Brain bank, Tissue bank, Biomaterial supply resource, Material storage repository |
| Application | Research |
| ID | See Full Record |
| Location | University of California at Los Angeles; California; USA,US Biobank Address:Building 212 Room 16, VA Greater Los Angeles Healthcare System, West Los Angeles Healthcare Center, 11301 Wilshire Blvd.(127A), Los Angeles, CA 90073 Phone: (310) 268-3536 Fax: (310) 268-4768 Email:brainbnk@ucla.edu |
| Name | Human Brain and Spinal Fluid Resource Center |
| Organism | Human |
| Keywords | Tissue, pre-mortem brain, post-mortem brain, Spinal cord, Cerebral Spinal Fluid, Serum, Blood cell, Urine, Blood |
| Condition | |
|---|---|
| Description | The BDSC collects, maintains, and distributes genetically defined strains of Drosophila melanogaster with significant research value. Emphasis is placed on genetic tools that are useful to a broad range of investigations. These include basic stocks of flies used in genetic analysis such as marker, balancer, mapping, and transposon-tagging strains; mutant alleles of identified genes, including a large set of transposable element insertion alleles; defined sets of deficiencies and a variety of other chromosomal aberrations; engineered lines for somatic and germline clonal analysis; GAL4 and UAS lines for targeted gene expression; enhancer trap and lacZ-reporter strains with defined expression patterns for marking tissues; and a collection of transposon-induced lethal mutations. Approximately 29,000 fly strains are currently available. Up-to-date stock lists are available for searching, browsing, or downloading/copying at the Internet site. An order form is available on the same site. One small subculture is provided of each requested stock. Larger quantities of animals cannot be provided by the center. Requests may be submitted via a web-based automated ordering system. Stock center scientists are available to answer questions about center stocks, use of the database, or general questions about Drosophila genetics for researchers new to the field. New users of the collection must contact the center for a Bloomington user number (BUN) before ordering stocks. Sponsors: The Bloomington Drosophila Stock Center collects, maintains and distributes Drosophila melanogaster strains for research. The Center is supported by grants from the National Science Foundation's Living Stock Collections Program (Grant No. 0841154), the National Institutes of Health's National Center for Research Resources (via NSF Grant No. 0841154), the National Institute of General Medical Sciences (via NSF Grant No. 0841154), the National Institute of Child Health and Human Development (via NSF Grant No. 0841154, Indiana University, and fees from users of the collection (50% of Center direct costs are provided by user fees). |
| Sample Type | |
| Processing | |
| Availability | |
| Type | Biomaterial supply resource |
| Application | |
| ID | See Full Record |
| Location | Indiana University; Indiana; USA |
| Name | Bloomington Drosophila Stock Center |
| Organism | Drosophila melanogaster |
| Keywords | Drosophila melanogaster, Element, Fly, Gene, Genetic, Genetic analysis, Allele, Animal, Chromosome, Database, Deficiency, Germline, Insertion, Invertebrate, Research, Scientist, Somatic, Stock center, Tagging, Transposon |
